Jun 5, 2025
With a commercially available chiral ferrocene-based phosphine–oxazoline ligand, we have realized an efficient rhodium-catalysed enantioselective hydrosilylation of unactivated alkenes, delivering Si-stereogenic monohydrosilanes in high yields and excellent enantioselectivities. Congrats to Prof Wu and Hao-Yang! Great collaboration with Prof. Qian Peng and Heng Zhang.
Check out here: https://pubs.rsc.org/en/content/articlelanding/2025/sc/d5sc02711j.
May 2025
Congrats to Xiao-Xue Nie (聂晓雪), Shuo Song (宋硕), Hua-Chen Shen (沈华宸) who successfully defended their PhD thesis. Congrats to Yu-Qing He (何雨晴), Chen-Kai Luo (骆辰恺), Xin-Lai (赖新), Xiao-Xuan Zeng (曾晓萱) who successfully defended their MS thesis.
April 28, 2025
Congrats to Shi-Hao, we report the Cu-catalyzed asymmetric carbene insertion into both Ge–H and Si–H bonds with α-trifluoromethyl diazo compounds, enabled by a class of newly developed C2-symmetrical bisoxazoline ligands (SPSiBox). The final version of this manuscript out in J. Am. Chem. Soc.
Check out here: https://pubs.acs.org/doi/10.1021/jacs.5c02996.
Also see the preprint in Chemrxiv on Feb 01, 2024: https://chemrxiv.org/engage/chemrxiv/article-details/65ba50039138d231611da968.
Feb 14, 2025
With a chiral monoprotected amino acid (MPAA) ligand and a racemic transient norbornene mediator, we have realized a rare atroposelective remote meta-C–H functionalization of heteroarene-containing biaryls. The final version of this manuscript out in J. Am. Chem. Soc. Congrats to Jian-Jun.
Check out here: https://pubs.acs.org/doi/10.1021/jacs.4c15491.
Feb 7, 2025
With a bulky acac-type ligand (Amacac), Ni(II)-catalyzed dicarbofunctionalization of alkenyl alcohols with aryl/alkenyl boronic acids and alkyl halides as the coupling partners has been realized using alcohol as the native directing group. The final version of this manuscript out in Chem Catal. Congrats to Li-Qin.
Check out here: https://www.sciencedirect.com/science/article/pii/S2667109324004706.
Also see the preprint in Chemrxiv on Aug 29, 2024: https://chemrxiv.org/engage/chemrxiv/article-details/66ced2d520ac769e5f16bbd7.
Jan 16, 2025
Collaborated with Prof. Shi-Liang Shi, we report the Hydroarylation of 1,1-disubstituted alkenes using a Ni/diimine catalytic system. The final version of this manuscript out in JACS.
Check out here: https://pubs.acs.org/doi/10.1021/jacs.4c17313.
Dec 18, 2024
We report the synthesis of diverse azaheterocycles and oxaheterocycles via Pd-catalyzed migratory 1,1-cycloannulation reaction (MCAR) of unactivated alkenes. The final version of this manuscript out in JACS. Congrats to Jin-Ping.
Check out here: https://pubs.acs.org/doi/10.1021/jacs.4c14153.
Also see the preprint in Chemrxiv on Sept 26, 2024: https://chemrxiv.org/engage/chemrxiv/article-details/66e45cea51558a15efe0732b.
Nov 28, 2024
With a bulky acac-type ligand, we have realized the Ni(II)-catalysed dicarbofunctionalisation of unactivated alkenes with aryl/alkenyl boronic acids and alkyl halides as the coupling partners with a diverse range of native functional groups as the directing group. Congrats to Dao-Ming. Great collaboration with Prof. Li-Ping Xu. Just out in Nat. Commun.
Check out here: https://www.nature.com/articles/s41467-024-54170-9.
Also see the preprint in Chemrxiv on April 16, 2024: https://chemrxiv.org/engage/chemrxiv/article-details/661d651b91aefa6ce19ed528.
Nov 22, 2024
Congrats to Muhammad Faisal Yasin who successfully defended his MS thesis.
Nov 18, 2024
Congrats to Dao-Ming Wang (王道明) who successfully defended his PhD thesis.
Oct 15, 2024
We report the coupling of azoles and azine N-oxides with Fischer copper carbene species bearing an α-siloxy group (in situ generated from acylsilanes catalytically under photoirradiation). Mechanistically, this reaction may undergo a bimetallic relay process. Congrats to Long. Just out in Adv. Sci.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/advs.202409457.
Sept 19, 2024
We report the preparation of lactones via Ni-catalyzed alkene hydroxylarylation and sequential intramolecular lactonization with O2 as a green oxidant and oxygen source. Congrats to Dao-Ming. Just out in Org. Lett.
Check out here: https://pubs.acs.org/doi/full/10.1021/acs.orglett.4c03108.
Sept 04, 2024
Congrats to Hua-Chen for his first publication in Chem. Sci. We report an efficient meta-C−H arylation of both phenylethyl and benzylicalcohols and their hydroxylamine derivatives using a readily removable oxime ether directing group. Great collaboration with Jin.
Check out here: https://doi.org/10.1039/D4SC03802A.
Aug 26, 2024
Congrats to Ze-Dong for his latest publication in Org. Lett. We have developed a new class of diphosphine ligands based on SPOSiOL (SPOSiP).
Check out here: https://pubs.acs.org/doi/full/10.1021/acs.orglett.4c02784
Aug 23, 2024
Welcome visiting student Zi-Yi Liu (刘子逸) from Nanjing University to the Wang group.
Aug 20, 2024
Welcome our new graduate student Ke Feng (冯可) from Hangzhou Institute for Advanced Study (UCAS) to the Wang group.
July 26, 2024
Pd-Catalyzed Hiyama-Type coupling of thianthrenium and phenoxathiinium salts has been realized. Just out in Org. Lett. Congrats to Zhi-Wei.
Check out here: https://pubs.acs.org/doi/10.1021/acs.orglett.4c02348.
July 8, 2024
Welcome Dr Ling-Feng Jiang (江岭峰) from Shanghai Normal University and Dr Ming-Qin Huang (黄明琴) from Nankai University to join the Wang group.
June, 2024
Congrats to Fei-Hu Gou (苟飞虎), Ying-Chao Li (李英超), Hao-Yang Qian (钱昊洋), Hao Li (李豪), Ze-Dong Li (李泽东) who successfully defended their MS thesis.
April 25, 2024
The 10th Org. Lett. paper from the Wang group is online now. Congrats to Dao-Ming and Lei! We report a Pd-catalyzed 1,2-oxyarylation of alkenes with O-acylhydroxylamines as an oxidant and an oxygen source.
Check out here: https://pubs.acs.org/doi/full/10.1021/acs.orglett.4c00285.
April 12, 2024
Congrats to Fei-Hu for his latest publication in Angew. Chem. Int. Ed. We have demonstrated a catalytic kinetic resolution strategy for the access of chiral Si-stereogenic silanes.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202404732.
March 14, 2024
Congrats to Jiang-Lin and Prof. Yichen Wu for their latest review paper on catalytic nitrogen–nitrogen bond formation reactions. Just accepted in ACS. Catal.
Check out here: https://pubs.acs.org/doi/full/10.1021/acscatal.4c00718.
Feb 27, 2024
The 10th ACIE paper from the Wang group is online now. Congrats to Jia-Hui and Long! We have demonstrated the construction of Si-stereogenic silanols via Pd-catalyzed enantioselective C–H alkenylation.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202402612.
Feb 04, 2024
Pd-catalyzed Si–O formation reaction via a Si–C activation approach with 100% atom-economy by employing silacyclobutanes (SCBs) and various hydroxy-containing substrates, including water, alcohols, phenols, and silanols. Just accepted in Sci. China Chem. Congrats to Shuang!
Check out here: https://www.sciengine.com/SCC/doi/10.1007/s11426-024-1951-0.
Nov 20, 2023
The nickel-catalyzed migratory β-selective hydroarylation and hydroalkenylation of alkenyl ketones and alkenyl heteroarenes has been realized with aryl boronic acids using alkyl halide as the mild hydride source. Just out in Angew. Chem. Int. Ed. Congrats to Hua-Dong and Ravi! Great collaboration with Prof. Zhong-Yan Cao.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202313336.
Oct 19, 2023
We have summarized the catalytic asymmetric synthesis of silicon-stereogenic organosilanes. Just out in Chem. Congrats to Yichen and Long.
Check out here: https://www.cell.com/chem/fulltext/S2451-9294(23)00479-5.
July 15, 2023
Our JACS paper regarding Cu-Mediated Thianthrenation and Phenoxathiination of Arylborons has been highlighted by Chem.
Check out here: https://www.cell.com/chem/fulltext/S2451-9294(23)00316-9.
July 11, 2023
With the assistance of a bulky acac-type ligand, we have developed a Ni(II)-catalyzed hydroxylarylation of alkenes with molecular oxygen. Congrats to Dao-Ming.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202304573.
Also see preprint: Chemrxiv 2023, DOI: 10.26434/chemrxiv-2023-0kcb5.
May 22, 2023
We have developed a class of diphosphine ligands based on SPSiOL with a large dihedral angle (SPSiP). Just out in Org. Lett. Congrats to Hao.
Check out here: https://pubs.acs.org/doi/10.1021/acs.orglett.3c01193.
Also see preprint: https://chemrxiv.org/engage/chemrxiv/article-details/6435a036a41dec1a56e3a453.
Apr 26, 2023
Congrats to Xiao-Yue and Ya-Ning for their latest publication in J. Am. Chem. Soc.
We have developed a Cu-Mediated Thianthrenation and Phenoxathiination of Arylborons.
Check out here: https://pubs.acs.org/doi/full/10.1021/jacs.3c03413.
Also see preprint: Chemrxiv 2022, DOI: 10.26434/chemrxiv-2022-4jd98.
Apr 5, 2023
Delighted to share this concept for radical-radical coupling. Just out in Chin. J. Chem. Congrats to Xiao-Yue.
Check out here: https://onlinelibrary.wiley.com/doi/10.1002/cjoc.202300188.
March 15, 2023
We have demonstrated the diverse synthesis of alkenylsilanes via Pd-catalyzed alkenyl C–H silylation. Just out in Org. Lett. Congrats to Zi-Hang!
Check out the manuscript here: https://pubs.acs.org/doi/10.1021/acs.orglett.3c00633.
Feb 26, 2023
Welcome our first international student Faisal from Pakistan to the Wang Group!
Feb 24, 2023
Welcome visiting student Fei Ren (任斐) from Changchun University of Technology to the Wang Group!
Feb 16, 2023
Welcome our new graduate student Xiao-Xuan Zeng (曾晓萱) to the Wang Group. Xiao-Xuan has completed her undergraduate work at Sichuan Normal University.
Jan 18, 2023
Congrats to Tao, Xin-Rui, and Shuo for their latest publication in Angew. Chem. Int. Ed.
With a newly developed SPSiOL-base bisphosphite ligand (SPSiPO), we have demonstrated a Ni-catalyzed asymmetric hydrosilylation of 1,1-disubstituted allenes for the first time, delivering the enantioenriched allylsilanes bearing a tertiary carbon stereocenter in high efficiency and 100% atom-economy. Great collaboration with Prof. Li-Ping Xu.
Check out the manuscript here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202216878.
Dec 05, 2022
Congrats to Long and Xueying for their latest publication in Angew. Chem. Int. Ed.
We have developed a Cu-catalyzed coupling reaction of acylsilanes with alkynes under photoirradiation via a in-situ generated Fischer-type copper carbene species. The side-arm modified bisoxazoline (SaBox) ligands prove to be crucial for this reaction, which provides the corresponding alkynyl alcohols in high yields with remarkable heterocycle tolerance and broad substrate scope. Great collaboration with our colleague Prof. Xiao-Song Xue.
Check out the manuscript here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202216373.
Nov 12, 2022
Congrats to Dao-Ming and Li-Qin for their latest publication in Nat. Commun.
We have identified a Adacac ligand, which could enable the Ni-catalyzed hydroarylation and hydroalkenylation of internal alkenes with organoborons under redox-neutral conditions.
Check out the manuscript here: https://www.nature.com/articles/s41467-022-34675-x.
Also see the preprint: Researchsquare 2022, DOI: 10.21203/rs.3.rs-1858346/v1.
Aug 27, 2022
Our proof-of-concept work on Migartory CycloAnnulation Reaction (MCAR) using a Pd catalyst for the efficient construction of azaheterocycles gets publicated in Nat. Commun. Congrats to Jin-Ping!
Check out the manuscript here: https://www.nature.com/articles/s41467-022-32726-x
Also see the preprint: Researchsquare 2022, DOI: 10.21203/rs.3.rs-1489059/v1.
June 28, 2022
We have summarized the recent advances in thianthrenation/phenoxathiination enabled site-selective functionalization of arenes. Just out in Synthesis. Check out the manuscript here: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0041-1737493
June 13, 2022
Welcome our new graduate student Li-Qin She (佘俐钦) and Shi-Hao Chen (陈诗豪) to the Wang Group. Li-Qin got his BS degree at Jilin University and has completed her undergraduate work at SIOC with Prof. Peng Wang. Shi-Hao got his BS degree at Lanzhou University and has completed his undergraduate work at SIOC with Prof. Guosheng Liu.
June 11, 2022
Congrats to Hong-Chao Chen (陈宏超) who successfully defended his MS thesis. Best of luck in your next journey at Shanghai Jiaotong University.
May 31, 2022
Congrats to Zi-Yu Dong (董梓钰) who successfully defended his MS thesis. Best of luck in your next adventure.
May 20, 2022
Our first Minireview is out in Angewandte. We have summarized the synthesis and applications of silicon-stereogenic monohydrosilane. Congrats to Yichen.
Check out the manuscript here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202205382
May 19, 2022
Congrats to Zi-Yang Chen (陈梓洋) who successfully defended his MS thesis. Best of luck in your in your next journey at South China University of Technology.
March 3, 2022
Welcome our new graduate student Hao-Yang Qian (钱昊阳) to the Wang Group. Hao-Yang has completed her undergraduate work at Nanjing University of Chinese Medicine working on biomedicine.
Feb 8, 2022
Welcome our new graduate student Fei-Hu Gou (苟飞虎) to the Wang Group. Fei-Hu has completed his undergraduate work at Zunyi Medical University working on nickel-catalyzed coupling reaction.
Nov 18, 2021
Congrats Lei Yang for her latest publication in Chem. Commun. We have developed a concise route to construction of enantiopure spirobiphenoxasilin-diol (SPOSiOL).
Check out here: https://pubs.rsc.org/en/Content/ArticleLanding/2021/CC/D1CC05576C.
Nov 3, 2021
Check out our latest publication in Angewandte regarding the asymmetric synthesis of Si-stereogenic cyclic monohydrosilanes. Congrats to Yu-Hao and Yichen! Great collaboration with Prof. Qian Peng at NKU.
Check out this manuscript here: https://onlinelibrary.wiley.com/doi/10.1002/anie.202113052.
Oct 18, 2021
Congrats to Yu-Lan for her latest publication in Org. Lett. We have developed a new approach for the efficient synthesis of alpha-amino azines.
Check out this manuscript here: https://pubs.acs.org/doi/full/10.1021/acs.orglett.1c03229.
Oct 11, 2021
Congrats to Long and Xiao-Xue for their latest publication in Eur. J. Org. Chem. An invited review regarding construction of Si-stereogenic silanes through C−H activation approach.
Check out here: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202101084.
This article also appears in: Silicon Chemistry in Organic Synthesis
Sept 5, 2021
Welocome our new PhD candidate Shuang Liu (刘爽) to the Wang Group. Shuang has obtained his MS degree at Zhengzhou University working on transition metal-catalyzed C-H functionalization.
Jun 11, 2021
Welcome our new graduate student Qing-Yan Wu (吴鲭彦) to the Wang Group. Qing-Yan has completed her undergraduate work at Guangxi University. Let us start the new adventure in organic chemistry.
May 2021
Congrats to Yu-Hao Huang (黄宇豪), Lei Yang (杨蕾) and Yu-Lan Zhang (张雨兰) who successfully defended their MS thesis. Best of luck in your next adventure.
Feb 20, 2021
Welcome visiting students Ruo-Yu Zhang (张若愚) and Peng-Gang Zhao (赵鹏刚) from Lanzhou University to the Wang Group!
Sept 24, 2020
Congrats to Xiao-Xue for her latest publication in Org. Lett. The alpha-arylation of carbonyl compounds with simple arenes are achieved using thianthrenium salts as the traceless arylating reagents. This protocol could tolerate the heterocyclic carbonyl compounds and complex bioactive molecules, which is appealing for medicinal chemistry.
Check out this manuscript here: https://pubs.acs.org/doi/10.1021/acs.orglett.0c02913.
Featured in Org. Chem. Highlights: Substituted Benzenes: https://www.organic-chemistry.org/Highlights/2021/14June.shtm.
Aug 10, 2020
The thianthrene S-oxide (TTSO)-mediated site-selective silylation of arenes has been realized via a thianthrenation/Pd-catalyzed silylation sequence. This manuscript gets accepted for publication in Org. Lett. Congrats to Yichen!
Check out this manuscript here: https://pubs.acs.org/doi/10.1021/acs.orglett.0c02458.
Aug 3, 2020
Congrats to Dao-Ming for his latest publication in Angew. Chem. We reported the discovery of a redox-neutral NiII/NiII catalytic cycle which is capable of the linear-selective hydroarylation of unactivated alkenes with arylboronic acids.
Check out this manuscript here: https://www.onlinelibrary.wiley.com/doi/10.1002/anie.202009195.
Highlighted by Synpacts, see: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1706516.
May 2020
Congrats to MS student Xin Chang (常鑫) who successfully defended her thesis. Best of luck in your next adventure in Viva Biotech (Shanghai) .
April 7, 2020
Check out our first Chem. Commun. entitled “para-selective arylation and alkenylation of monosubstituted arenes using thianthrene S-oxide as a transient mediator”. Congrats to Xiao-Yue!
Check out here: https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc00641f#!divAbstract.
Mar 6, 2020
Taking advantage of the unique properties of Si, we have designed a chiral Si-centered spirocycle scaffold (SPSiOL) for chiral catalyst and ligand development. Accordingly, we have developed a method for the asymmetric synthesis of chiral spirosilabiindanes. The preliminary results just get accepted in Angew. Chem. Congrats to Xin and Pei-Long!
Check out this manuscript here: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202002289.
Nov 2019
Dr. Wang recently won the 2020 Thieme Chemistry Journal Award. This award is presented every year to up-and-coming researchers worldwide who are in the early stages of their independent academic career as assistant or junior professors. The awardees are selected exclusively by the editorial board members of SYNTHESIS, SYNLETT, and SYNFACTS who constantly watch out for promising, young individuals working in chemical synthesis and catalysis or closely related areas of organic chemistry.
Also see: https://www.thieme.de/en/thieme-chemistry/thieme-chemistry-journals-award-107359.htm
Nov 15, 2019
Para-Selective Borylation of Monosubstituted Benzenes via a Transient Mediator approach. WHY para? Magic thianthrene dication. Congrats Jie and Xiaoyue.
Check out this manuscript here: https://link.springer.com/article/10.1007/s11426-019-9652-x
The work first appeared on ChemRxiv back in May. Check out the pre-print here: https://chemrxiv.org/engage/chemrxiv/article-details/60c7463e702a9bc38918ab66
Oct 18, 2019
Jin-Feng has developed a method to introduce azaheterocycles in arenes, providing an aversatile method for the synthesis of pharmaceutically important N-(hetero)arylated heteroarenes. Great collaboration with Jin. This work finally gets accepted in Angew. Chem. Congrats to Jin-Feng and Jian-Jun.
Check out this manusript here: https://onlinelibrary.wiley.com/doi/10.1002/anie.201910395
Feb 20, 2019
Our first paper entitled “Synthesis of β-Arylethenesulfonyl Fluoride via Pd-Catalyzed Nondirected C–H Alkenylation” gets accepted in Org. Lett. Congrats to Xiao-Yue and Yichen.
Check out this manuscript here: https://pubs.acs.org/doi/10.1021/acs.orglett.9b00165
May 2018
Our group is loacted at room 1510, Building 2 (君谋楼).
Jan 2018
We are here (SIOC in Shanghai).
The Wang Group 